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Mouse monoclonal antibody Anti-Human DDX48

Catalog No. BMR00422 ¡Î2256C1¡Ï Data Sheet  

¢£Background 
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [NCBI Entrez Gene Summary]

¢£Quality of Control
Western blot analysis of immunized recombinant protein, using anti-DDX48 monoclonal antibody.


Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Antibody Concentration 100 μg/ml (1.0 ml)
Host Species Human
Preparation This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility Filtered through a 0.22 μm membrane.
Alternate Names EIF4A3,NUK-34, hNMP265, KIAA0111,MGC10862, eIF4AIII
Accession No. NM_014740
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Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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