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Mouse monoclonal antibody Anti-Human SMAD4

Catalog No. BMR00621 ¡Î188C1a¡Ï Data Sheet  

¢£Background 
Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor.[UniProtKB Function]

¢£Quality of Control
Western blot analysis of immunized recombinant protein, using anti-SMAD4 monoclonal antibody.


Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Antibody Concentration 100 μg/ml (1.0 ml)
Host Species Human
Preparation This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility Filtered through a 0.22 μm membrane.
Alternate Names JIP, DPC4, MADH4
Accession No. NM_005359
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Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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