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Mouse monoclonal antibody Anti-Human HMGA2
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| This gene encodes a protein that belongs to the non-histone chromosomal high
mobility group (HMG) protein family. HMG proteins function as architectural factors
and are essential components of the enhancesome. This protein contains structural
DNA-binding domains and may act as a transcriptional regulating factor.
Identification of the deletion, amplification, and rearrangement of this gene that are
associated with myxoid liposarcoma suggests a role in adipogenesis and
mesenchymal differentiation. A gene knock out study of the mouse counterpart
demonstrated that this gene is involved in diet-induced obesity. Alternate
transcriptional splice variants, encoding different isoforms, have been characterized.[NCBI Entrez Gene Summary] |
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Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-HMGA2 mAb. [Lot No. 2421C6a-1] |
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Immunocytochemistry protocol
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Western blot analysis of immunized recombinant protein, using anti-HMGA2 monoclonal antibody.
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids. |
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| Antibody Concentration |
100 μg/ml (1.0 ml) |
| Host Species |
Human |
| Preparation |
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Sterility |
Filtered through a 0.22 μm membrane. |
| Alternate Names |
BABL, LIPO, HMGIC, HMGI-C, STQTL9 |
| Accession No. |
NM_003483 |
| Purchase |
Ordering information
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| Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off . |
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FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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