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Mouse monoclonal antibody Anti-Human NFKB2
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| NFKB has been detected in numerous cell types that express cytokines,
chemokines, growth factors, cell adhesion molecules, and some acute phase
proteins in health and in various disease states. NFKB is activated by a wide variety
of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet
irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B
has been linked to inflammatory events associated with autoimmune arthritis,
asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS.
In contrast, complete and persistent inhibition of NF-kappa-B has been linked
directly to apoptosis, inappropriate immune cell development, and delayed cell
growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996)
[PubMed 8717528].[supplied by OMIM][NCBI Entrez Gene Summary] |
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Western blot analysis of immunized recombinant protein, using anti-NFKB2 monoclonal antibody.
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids. |
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| Antibody Concentration |
100 μg/ml (1.0 ml) |
| Host Species |
Human |
| Preparation |
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Sterility |
Filtered through a 0.22 μm membrane. |
| Alternate Names |
LYT10, LYT-10 |
| Accession No. |
BC002844 |
| Purchase |
Ordering information
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| Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off . |
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FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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