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Mouse monoclonal antibody Anti-Human ERCC5

Catalog No. BMR00683 ¡Î2328C1a¡Ï Data Sheet  

¢£Background 
Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined.[NCBI Entrez Gene Summary]

¢£Quality of Control
Left : Western blot analysis of immunized recombinant protein, using anti-ERCC5 monoclonal antibody. Right : CBB staining of immunized recombinant protein.


Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Antibody Concentration 100 μg/ml (1.0 ml)
Host Species Human
Preparation This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility Filtered through a 0.22 μm membrane.
Alternate Names XPG, UVDR, XPGC, COFS3, ERCM2
Accession No. NM_000123
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Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off .
FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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