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Mouse monoclonal antibody Anti-Human GCN5L2
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| Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones
gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with
core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral
protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral
genes.[UniProtKB Function] |
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Western blot analysis of immunized recombinant protein, using anti-GCN5L2 monoclonal antibody.
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids. |
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| Antibody Concentration |
100 μg/ml (1.0 ml) |
| Host Species |
Human |
| Preparation |
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
| Sterility |
Filtered through a 0.22 μm membrane. |
| Alternate Names |
GCN5, hGCN5, PCAF-b, MGC102791 |
| Accession No. |
NM_021078 |
| Purchase |
Ordering information
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| Caution must be taken to avoid contact with skin or eyes. In such a case, rinse thoroughly at once with water. Do not ingest, inhale, or swallow. Seek medical attention immediately. Wear appropriate protective clothing such as laboratory overalls, safety glasses and gloves. It is strongly advised that this product should be handled by people who have been well trained in laboratory techniques and that it is handled with care pursuant to the principles of good laboratory practice. All chemicals are deemed potentially harmful. The vial is prone to fall over. Use caution, especially when the lid is off . |
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FOR RESEARCH USE ONLY, NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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